Mame Biram Diouf scored a sensational solo goal, as Stoke City defeated Manchester City 1-0 at the Etihad on Saturday.
Manuel Pellegrini’s men failed to take advantage of their superiority in the first half and nine minutes into the second half, the Senegalese striker broke away, evading several challenges to slot past Joe Hart.
The loss represents the first defeat for the current champions, who won their first two matches against Newcastle and Liverpool.
Diego Costa helped himself to a brace, as Chelsea beat Everton 6-3 at Goodison Park, to go top of the table with nine maximum points.
In other games of the day, Morgan Schneiderlin also scored twice as Southampton won 2-1 away to West Ham. Wilfried Zaha scored a late, late leveller, as Crystal Palace held Newcastle to 3-3 draw at St James.
Swansea continued their fine run of form with a 3-0 hammering of West Brom, while Harry Redknapp’s QPR grabbed their first win of the season at home to Sunderland