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Wednesday, August 27, 2014

Know your risk for ovarian cancer..Must Read


Cancer
Current research suggests ovarian cancer begins in the fallopian tubes and moves to the ovaries, the twin organs that produce a woman’s eggs and the main source of the female hormones estrogen and progesterone. Treatments for ovarian cancer have become more effective in recent years, with the best results seen when the disease is found early.
The vast majority of ovarian cancers are epithelial ovarian carcinomas. These are malignant tumours that form from cells on the surface of the ovary. Some epithelial tumours are not clearly cancerous. These are known as tumours of low malignant potential. LMP tumours grow more slowly and are less dangerous than other forms of ovarian cancer.
Ovarian cancer can be a frightening diagnosis, with five-year relative survival rates that range from 89 per cent to 18 per cent for epithelial ovarian cancer, depending on the stage when the cancer was found. For LMP tumors, the five-year relative survival rates range from 99 per cent to 77 per cent.
The symptoms of ovarian cancer include bloating or pressure in the belly, pain in the abdomen or pelvis, feeling full too quickly during meals, urinating more frequently.
However, women who have biological children are less likely to get ovarian cancer than women who have never given birth. The risk appears to decrease with every pregnancy, and breastfeeding may offer added protection.
Ovarian cancer is also less common in women who have taken birth control pills. Women who have used the pill for at least five years have about half the risk of women who never took the pill. Like pregnancy, birth control pills prevent ovulation. Some researchers think ovulating less often may protect against ovarian cancer.
Also, getting your tubes tied, formally known as tubal ligation, may offer some protection against ovarian cancer. The same goes for having a hysterectomy – removing the uterus.
For women with genetic mutations that put them at high risk for ovarian cancer, removing the ovaries is an option. This can also be considered in women over 40 getting a hysterectomy.
While there is no definitive diet to prevent ovarian cancer, there is evidence that what you eat can make a difference. In one recent study, women who stuck to a low-fat diet for at least four years were less likely to develop ovarian cancer. Some researchers report the cancer is also less common in women who eat a lot of vegetables.
Researchers are working on therapies that target the way ovarian cancer grows. A process called angiogenesis involves the formation of new blood vessels to feed tumors. A drug called Avastin blocks this process, causing tumours to shrink or stop growing. Avastin is approved for other cancers, but ovarian cancer researchers are still testing this therapy, which can have serious side effects.
Here are some factors that increase a woman’s chances of developing ovarian cancer
Family history
A woman’s odds of developing ovarian cancer are higher if a close relative has had cancer of the ovaries, breast, or colon. Researchers believe that inherited genetic changes account for 10 per cent of ovarian cancers. This includes the BRCA1 and BRCA2 gene mutations, which are linked to breast cancer. Women with a strong family history should talk with a doctor to see whether closer medical follow-up could be helpful.
Age
The strongest risk factor for ovarian cancer is age. It’s most likely to develop after a woman goes through menopause. Using postmenopausal hormone therapy may increase the risk. The link seems strongest in women who take estrogen without progesterone for at least five to 10 years. Doctors are not certain whether taking a combination of estrogen and progesterone boosts the risk as well.
Obesity
Obese women have a higher risk of getting ovarian cancer than other women. And the death rates for ovarian cancer are higher for obese women too, compared with non-obese women. The heaviest women appear to have the greatest risk.
After surgery
When women have both ovaries removed, they can no longer produce their own estrogen. This triggers menopause, no matter how young the patient. The drop in hormone levels can also raise the risk for certain medical conditions, including osteoporosis. It’s vital that women have regular follow-up care after being treated for ovarian cancer.
Women may find that it takes a long time for their energy to return after treatments end. Fatigue is a very common problem after treatment for cancer. Beginning a gentle exercise program is one of the most effective ways to restore energy and improve emotional well-being. Check with your health care team to determine which activities are right for after surgery.

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