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Monday, February 2, 2026

WHAT IS ERECTILE DYSFUNCTION ?

 

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## **Erectile Dysfunction (ED)**


**Erectile Dysfunction (ED)** is the persistent inability to attain or maintain an erection sufficient for satisfactory sexual performance. It is a common medical condition that affects men of all ages but becomes more prevalent with advancing age. ED is not merely a sexual problem; it is often an early indicator of underlying systemic diseases.


### **Epidemiology**


Erectile dysfunction affects millions of men worldwide. Studies show that up to **50% of men over 40 years** experience some degree of ED, with prevalence increasing with age and the presence of chronic medical conditions.


### **Pathophysiology**


A normal erection requires the coordinated interaction of:


* Intact vascular supply

* Functional nerves

* Adequate hormonal levels

* Psychological readiness


Erectile dysfunction occurs when there is impairment in any of these mechanisms, particularly reduced penile blood flow, endothelial dysfunction, or disrupted neural signaling.


### **Causes of Erectile Dysfunction**


#### **Organic Causes**


* **Vascular disorders:** Hypertension, atherosclerosis, peripheral vascular disease

* **Endocrine disorders:** Diabetes mellitus, hypogonadism, hyperprolactinaemia, thyroid disorders

* **Neurological conditions:** Stroke, spinal cord injury, multiple sclerosis

* **Medications:** Antihypertensives, antidepressants, antipsychotics

* **Lifestyle factors:** Smoking, excessive alcohol use, obesity, physical inactivity


#### **Psychogenic Causes**


* Anxiety and depression

* Performance anxiety

* Relationship conflicts

* Stress and emotional trauma


*Many patients have a combination of organic and psychogenic factors.*


### **Clinical Presentation**


* Difficulty achieving or sustaining an erection

* Reduced rigidity or duration of erection

* Decreased sexual confidence

* Associated reduced libido or ejaculatory disorders


### **Diagnosis**


Evaluation of erectile dysfunction includes:


* Detailed medical, sexual, and psychosocial history

* Physical examination (cardiovascular, endocrine, and genital systems)

* Laboratory investigations:


  * Fasting blood glucose

  * Lipid profile

  * Serum testosterone

  * Prolactin and thyroid function tests (where indicated)


### **Management**


Treatment should be individualized and directed at the underlying cause.


#### **Lifestyle Modification**


* Smoking cessation

* Weight reduction

* Regular physical exercise

* Reduction of alcohol intake

* Optimal control of diabetes and hypertension


#### **Pharmacological Therapy**


* **Phosphodiesterase-5 inhibitors (PDE-5 inhibitors):**


  * Sildenafil

  * Tadalafil

  * Vardenafil

  * Avanafil


These drugs enhance erectile response by increasing penile blood flow and require sexual stimulation to be effective.


#### **Hormonal Therapy**


* Testosterone replacement therapy in confirmed hypogonadism


#### **Psychological Therapy**


* Counseling and cognitive-behavioral therapy for psychogenic ED

* Couples therapy where necessary


#### **Advanced Therapies**


* Vacuum erection devices

* Intracavernosal injections

* Penile prosthesis surgery (for refractory cases)


### **Prevention**


* Healthy lifestyle choices

* Early detection and treatment of chronic illnesses

* Regular medical check-ups

* Open communication with healthcare providers


### **Conclusion**


Erectile dysfunction is a treatable medical condition with significant physical and psychological implications. Early evaluation and appropriate management not only restore sexual function but may also prevent serious cardiovascular and metabolic complications.

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