Amlodipine is a second-generation dihydropyridine calcium channel blocker that can cause gingival hypertrophy. The prevalence of amlodipine-induced gingival hypertrophy has been shown to be between 1.7% and 3.3%.
Nifedipine is one of the commonest antihypertensive drugs (calcium channel blockers) used to treat hypertension and some forms of angina. Though it has various side effects, gingival enlargement is the most attended side effect which is of great importance in dentistry.
In some patients (usually younger patients), tenderness, swelling, or bleeding of the gums (gingival hyperplasia) may appear soon after phenytoin treatment is started. To help prevent this, brush and floss your teeth carefully and regularly and massage your gums.
Doctors treating cluster headache with verapamil need to be aware of this side effect, especially as it may be preventable with good dental hygiene and dental plaque control, is reversible with reduction or cessation of verapamil, and can lead to dental loss.
Tetracycline doesn't only affect the color of teeth. Exposure to the antibiotic can also weaken tooth enamel, putting teeth at risk of decay (cavity). A cavity, or hole in the tooth, is permanent and requires a dental filling.
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