A married 30-year-old woman with no past medical history presents to the
emergency department with complaints of dull aching pain in the right
upper quadrant of her abdomen and her lumbar region. The discomfort was
initially associated with low-grade fevers that were relieved by
over-the-counter antipyretics. Recently, the fevers have only
temporarily been relieved with antipyretics.
These symptoms are
associated with nausea, vomiting, decreased appetite, yellowish
discoloration of the sclera (shown), and a 10-kg weight loss. The
patient denies any history of change in bowel habits, melena,
clay-colored stools, hematemesis, or other symptoms.
Her medical history includes cholecystitis during pregnancy, which
was managed with antibiotics. She subsequently had a caesarean section
and cholecystectomy. She is a nonsmoker and doesn't consume alcohol. She
denies any illicit drug use or any recent travel history and is a
resident of Pakistan. On examination, she is a young, anxious-appearing
woman, with a regular heart rate of 100 beats per minute, blood pressure
of 110/70 mm Hg, respiratory rate of 24 breaths per minute, and a
temperature of 102
oF. She is jaundiced. Abdominal examination
reveals right upper quadrant tenderness on deep palpation with tender
hepatomegaly. She has diminished breath sounds and dullness on
auscultating the right lower lung. The rest of her physical examination
is unremarkable.
The patient's laboratory results are shown. Which tests are abnormal?
There is a right-sided pleural effusion with blunting of the costophrenic angle (circled).
The pleural effusion is aspirated and sent to the laboratory for
analysis. Pleural effusions may be either transudative or exudative.
Light's criteria are used to differentiate between transudative and
exudative processes.
There are multiple hypodense lesions (circles) within the right lobe of
the liver that likely correlate with the abnormality seen on ultrasound.
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